Adjustment Disorder in People living with Chronic illness

Key things to know What the evidence shows
How common is it? Cancer: ~12.5–19.4% interview-defined AjD, depending study/meta-analysis
Is it more common among people living with chronic illness? Major diagnosis/treatment is a classic precipitating stressor
Are people living with chronic illness at higher risk? #N/A
How much higher is the risk? Cancer meta-analysis 19.4% oncology/hematology; 4-week pooled cancer estimate 12.5% in another review
How often can it be missed? Very High
Does it show up differently among people living with chronic illness? Very Strong Yes
How might it look different? Distress focused on diagnosis, prognosis, treatment, altered functioning/work/identity; must distinguish understandable disease distress from disorder
What commonly occurs alongside it? Depression; anxiety; PTSD
What can it be confused with? Expected distress after diagnosis; MDD; GAD; PTSD
Common screening tool ADNM-20 — Adjustment Disorder–New Module-20
Separate screening tool for people living with chronic illness ETAM — Adjustment Disorder Scale for Medically Ill Patients, emerging 2025 tool
1 of 14