Major Depressive Disorder in Older adults / Seniors

Key things to know What the evidence shows
How common is it? 13.3% global pooled MDD
Is it more common among older adults / seniors? Estimates highly variable; pooled MDD substantial
Are older adults / seniors at higher risk? Yes, clinically important
How much higher is the risk? Not established
How often can it be missed? High due to medical/cognitive symptom overlap
Does it show up differently among older adults / seniors? Yes
How might it look different? Somatic complaints, apathy, cognitive complaints, sleep problems
What commonly occurs alongside it? Anxiety; cognitive disorders; chronic medical illness
What can it be confused with? Dementia; delirium; medication effects; grief; medical illness
Common screening tool PHQ-9
Separate screening tool for older adults / seniors GDS / GDS-15
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