Schizophrenia in Menopausal / perimenopausal women

Key things to know What the evidence shows
How common is it? NE
Is it more common among menopausal / perimenopausal women? Clinically important worsening/late-onset period for some women
Are menopausal / perimenopausal women at higher risk? Yes — hormonal transition may affect course
How much higher is the risk? No clean prevalence RR; evidence supports symptom/treatment changes
How often can it be missed? High
Does it show up differently among menopausal / perimenopausal women? Strong Yes
How might it look different? Psychotic symptoms may worsen; antipsychotic response/side effects can change
What commonly occurs alongside it? Metabolic/cardiovascular disease; depression; cognitive problems
What can it be confused with? Mood disorder with psychosis; neurological/medical causes; medication effects
Common screening tool PQ-16 self-assessment → clinical evaluation
Separate screening tool for menopausal / perimenopausal women None
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