Schizophrenia in People living with Chronic illness

Key things to know What the evidence shows
How common is it? Not established schizophrenia-among-all-chronic-illness
Is it more common among people living with chronic illness? Schizophrenia is strongly associated with physical multimorbidity, reverse denominator
Are people living with chronic illness at higher risk? Strong comorbidity association
How much higher is the risk? Severe mental illness: physical multimorbidity OR 2.40 vs controls
How often can it be missed? High, especially when medical/medication causes can mimic psychiatric symptoms
Does it show up differently among people living with chronic illness? Yes contextually
How might it look different? Physical illness, medications and delirium can produce psychosis-like symptoms; schizophrenia also complicates medical care
What commonly occurs alongside it? Diabetes; cardiovascular/respiratory disease; metabolic disease
What can it be confused with? Delirium; medication-induced psychosis; neurological disease
Common screening tool PQ-16 self-assessment → clinical evaluation
Separate screening tool for people living with chronic illness None
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